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Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach.

机译：使用对乙酰氨基酚，胺碘酮和环孢菌素a作为模型化合物，在原代小鼠肝细胞中筛选药物诱导的肝毒性：一种由组学指导的方法。

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Van Summeren, A.; Renes, J.; Lizarraga, D.; Bouwman, F.G.; Noben, J.P.; van Delft, J.H.; Kleinjans, J.C.; Mariman, E.C.;
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年度 2013
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正文语种 en
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1. Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity [J] . Wim F.P.M. Van den Hof, Anke Van Summeren, Arjen Lommen Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2014,第Null期

机译：在原代小鼠肝细胞中的综合交叉组学分析揭示了环孢菌素A诱导的肝毒性机制
2. Potentiation of acetaminophen hepatotoxicity by doxapram in mouse primary cultured hepatocytes. [J] . Kanno S, Ishikawsa M, Takayanagi M, Biological & pharmaceutical bulletin . 2000,第4期

机译：多沙普仑在小鼠原代培养的肝细胞中增强对乙酰氨基酚的肝毒性。
3. Tolerance to Acetaminophen Hepatotoxicity in the Mouse Model of Autoprotection Is Associated with Induction of Flavin-Containing Monooxygenase-3 (FMO3) in Hepatocytes [J] . Swetha Rudraiah, Philip R. Rohrer, Igor Gurevich, Toxicological sciences: An official journal of the Society of Toxicology . 2014,第1期

机译：对乙酰氨基酚肝毒性的自动保护的小鼠模型的耐受性与肝细胞中含有黄素的单加氧酶3（FMO3）的诱导有关。
4. Repopulation of diseased mouse liver with rodent and human adult primary hepatocytes and long-term survival of transplanted hepatocytes in the uPA/RAG-2 mouse model [C] . M. DANDRI, M. R. BURDA, J. PETERSEN, International Congress on Thrombosis . 2002

机译：用啮齿动物和人成人原发性肝细胞的患病小鼠肝脏的重新迁移，upA / Rag-2小鼠模型中移植肝细胞的长期存活
5. Mechanisms of acetaminophen-induced hepatotoxicity: Role of mitochondrial permeability transition, reactive oxygen, and reactive nitrogen in freshly isolated mouse hepatocytes. [D] . Burke, Angela Shannon. 2007

机译：对乙酰氨基酚诱导的肝毒性机制：在新鲜分离的小鼠肝细胞中线粒体通透性转变，活性氧和活性氮的作用。
6. Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen Amiodarone and Cyclosporin A as Model Compounds: An Omics-Guided Approach [O] . Anke Van Summeren, Johan Renes, Daneida Lizarraga, -1

机译：使用对乙酰氨基酚胺碘酮和环孢菌素A作为模型化合物筛选原代小鼠肝细胞中药物诱导的肝毒性：一种由组学指导的方法
7. The secretome of primary human hepatocytes in an organotypic bioreactor culture for the identification of biomarkers of drug-induced hepatotoxicity [O] . Tascher Georg 2012

机译：在器官型生物反应器培养物中原代人肝细胞的分泌组用于鉴定药物诱导的肝毒性的生物标志物

Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach.

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